Author | : | van Leeuwen |
Binding | : | Hardback |
Edition | : | 1 |
Year | : | 2014 |
Pages | : | 610 |
ISBN | : | 9783131707710 |
$400.00
$400.00
Description
The two-volume set on C-1 Building Blocks in Organic Synthesis critically reviews the state of the art of a wide variety of reactions by which one carbon atom is added to an organic molecule, forming a C-C bond. In spite of the numerous classic reactions of this kind, there has been enormous progress in recent years, especially for those reactions involving catalytic methods. Introduction of substituted methyl groups is a major challenge and only very recently the first catalysts have been discovered that enable the introduction of fluoromethyl groups in aromatics.